Watsopano mayeso ntchito limodzi dontho la magazi kuulula zonse m'mbiri ya tizilombo matenda

New test uses a single drop of blood to reveal entire history of viral infections

 

Zoyendetsedwa ndi Guardian.co.ukNkhaniyi lotchedwa “Watsopano mayeso ntchito limodzi dontho la magazi kuulula zonse m'mbiri ya tizilombo matenda” linalembedwa ndi Ian Chitsanzo Science mkonzi, pakuti The Guardian Lachinayi 4 June 2015 18.00 UTC

Ofufuza anayamba wotsika mtengo ndipo mofulumira mayesero amene amafotokoza munthu wodzala mbiri ya tizilombo matenda limodzi lokha dontho la magazi.

Mayeso zimathandiza madokotala kuwerenga kuchokera pa mndandanda wa mavairasi amene kachilombo, kapena kupitiriza kuwononga, odwala ngakhale pamene iwo anachititsa aliyense waledzera.

Kagwiridwe zikutanthauza kuti GPS akanakhoza pounika odwala onse a mavairasi waluso matenda anthu. Izo zikhoza kusintha kuzindikira matenda aakulu monga matenda a chiwindi C ndi HIV, anthu akhoza kukwaniritsa kwa zaka mosadziwa.

"Mwachibadwa, pamene dokotala akufuna kudziwa ngati wina akhala HIV ndi kachilombo, iwo kulota zimene HIV ndi, ndipo taonani mwachindunji kuti kachilombo,"Anati Stephen Elledge, amene anatsogolera ntchito pa Brigham ndi Women a Hospital ku Boston.

"Zimenezi zingachititse kuti ndi matenda kumene anthu pachaka, adokotala komanso awo atamwa mbiri olembedwa. Iwo akanatha kupeza tizilombo matenda amene kwambiri ndipo kuti wodwala sankadziwa iwo anali,"Iye anati.

The (£ 16) chiyeso atamukoka pa patsogolo kupanga zinthu zamoyo mofulumira jini molumikiza yosanthula oposa 1000 tizilombo ta munthu mavairasi limodzi litapitirira. Mpaka pano, ambiri mayesero ndaliyembekezera okha limodzi HIV pa nthawi. Elledge linafotokoza kuti atsopano mayeso, wotchedwa VirScan, akhoza akumapanga 100 zitsanzo ziwiri kwa masiku atatu.

Mayeso amapezera mwayi kuti chitetezo cha m'thupi zimapangitsa chitetezo kumenyana mavairasi pamene thupi amakhala kachilombo. Izi chitetezo ndi moyo mu m'magazi kwa zaka zambiri.

Kukhala mayeso, Elledge adapanga magulu a wowona mavairasi kunyamula Akamva mapuloteni kwa anthu mavairasi zawo pamalo. Okwana, ananyamula mapuloteni ku oposa 1000 tizilombo ta pa 206 osiyanasiyana mavairasi kudziwika kuwononga anthu. Chitetezo ntchito mapuloteni zidutswa kuzindikira kuwukira mavairasi ndi kukhazikitsa awo kuukira.

Pamene droplet magazi wodwala wosakaniza ndi kusinthidwa mavairasi, aliyense chitetezo ali latch pa anthu HIV mapuloteni iwo amaona kuti ankhondowo. Asayansi ndiye taidule chitetezo ndi kupeza anthu mavairasi kwa mapuloteni zidutswa iwo ankadalira.

"Ndi nthawi yoyamba ife ndakwanitsa m'moyo kwathunthu osakondera mbali iliyonse njira zimene mavairasi ndi matenda anthu, ndipo ife tikhoza kuchita izo zonse kudziwika mavairasi,"Anati Elledge. Mayeso amanyamula ndi chitetezo munthu chimabala ku vaccinations, koma zikhoza anatayidwa ku zotsatira. Zafotokozedwa analembedwa magazini Science.

Mu chionetsero cha luso, gulu kusanthula magazi 569 anthu US, South Africa, Thailand ndi Peru. Mayeso anapeza kuti, pa avareji, anthu anali ndi kachilombo 10 mtundu wa mavairasi, Komabe ziwiri anthu mu mayesero anali mbiri ya 84 matenda osiyana siyana mavairasi.

The Matenda ambiri anali herpes mavairasi, amene amayambitsa zilonda, enteroviruses anakwiyitsa stomaches, fuluwenza, ndipo rhinoviruses amene amayambitsa wamba chimfine. Anthu mu US anaona ochepa matenda kuposa amene ali m'mayiko ena, ndipo ankayembekezera, Anthu achikulire anali umakhutiritsa atamwa mbiri kuposa achinyamata.

Mayeso kungabweretse zikuluzikulu phindu kwa chiwalo kumuika odwala. Mmodzi vuto kuti angatsatire kumuika opaleshoni zosayembekezereka reawakening cha mavairasi amene lurked anafooka mu wodwala kapena mwiniwake kwa zaka. Izi mavairasi akabweze ntchito pamene wodwala m'thupi ndi mumtima ndi mankhwala kuwaletsa kukana limba. Standard mayesero ambiri amalephela kukatenga zobisika mavairasi asanachite opareshoni, koma VirScan ndondomeko angathe kuvumbuuitsa pamaso pawo ndi maso madokotala ndi odwala kuopsa.

"Izi zikhoza kukhala wamtengo wapatali kwambiri,"Anati Iwijn De Vlaminck, ndi Biomedical zomangamanga pa Cornell University ku New York, amene sankachita nawo mu phunziro. "Kodi zimenezi zimathandiza inu kuchita ndi kuyang'ana zinthu zakale ndi kuyeza munthu kukhudzana ndi kale matenda. Amene ali ofunika ubwino, chifukwa mutha kuona matendawa amene amapita ku kachedwedwe. Mukhoza pounika magazi odwala ndi chiwalo amapereka chithandizo mu njira yotakata kwambiri ndi kuneneratu kuthekera m'tsogolo nkhani ndi tizilombo reactivation. "

Asayansi akukhulupirira mayeso adzaponyanso kumvetsa mmene tizilombo matenda odana anthu ooneka ngati zifukwa zina matenda m'tsogolo. Ena matenda kungachititse kuwonongeratu thupi minofu, kapena kusintha m'thupi, m'njira kusiya anthu kwambiri pa chiopsezo anoŵa pamene iwo ndi achikulire. Mwachitsanzo, matenda ndi Epstein-Barr HIV adzautsa kutenga khansara. Koma ena mavairasi bwanji kakatali thanzi kwambiri murkier. "Kuti ngati kusanthula chinachake ichi kwenikweni zimathandiza,"Anati Elledge.

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