tarukino Smoking nui-kaha kia tūkino weu io i roto i te roro

Smoking high-strength cannabis may damage nerve fibres in brain


Powered e Guardian.co.ukTēnei tuhinga ui “tarukino Smoking nui-kaha kia tūkino weu io i roto i te roro” e Ian etita Pūtaiao Tauira i tuhituhia, mo te Guardian ki te Paraire 27 Whiringa 2015 00.01 UTC

tarukino High-kaha kia tūkino muka karere e rahurahu te rere o ngā karere puta noa nga wahi e rua o te roro, titau pūtaiao. scans roro o te iwi nei paowa kaha wā kunuku-rite tarukino whakakitea rerekētanga mohio i roto i te mea ma i hono te maui, me te tika tuakoi, me waha ana tohu i tetahi taha o te roro ki te atu.

kihai i nga huringa kitea i roto i te hunga e kore nei e whakamahia ana tarukino ranei he paowa kau anake te momo iti puai o te tarukino, kitea nga kairangahau.

whakaaro te ako ki te hei i te tuatahi ki te titiro i te pānga o te tarukino mananga i runga i te hanganga roro, me kōrero kia whakamahi nui o kunuku meinga atu kino ki te io hono, hanga kōrero puta noa i tuakoi o te roro iti tōtika.

Paola Dazzan, he neurobiologist i te Institute o Psychiatry i College London a Kingi, ka mea puta nga pānga ki te kia hono ki te taumata o te whakauru kaha, tetrahydrocannabinol (THC), i roto i te tarukino. Ahakoa i roto i ngā tuku iho o te tarukino 2 ki 4 % THC, nga momo atu puai (o nei i reira e pā ana ki 100), Ka taea e roto 10 ki 14% THC, E ai ki te aroha DrugScope.

"Ki te titiro koe i te io hono, aha e te kitenga tatou ko te rerekētanga nui i roto i te mea ma i waenganui i te hunga e whakamahi tarukino mananga tiketike, me te hunga e kore e whakamahi i te tarukino, whakamahi ranei te raau taero iti-mananga,"Ka mea a Dazzan. He taonga i roto i te mau farii ohipa cannabinoid te io hono, i runga i nei i te mahi THC matū.

He ahua DTI o te io hono, rite kite i te taha, is shown in red on and superimposed on a background MRI image of the brain.
He ahua DTI o te io hono, rite kite i te taha, is shown in red on and superimposed on a background MRI image of the brain. Whakaahua: Institute of Psychiatry

“The difference is there whether you have psychosis or not, and we think this is strictly related to the potency of the cannabis,” she added. Details of the study are reported in the journal Psychological Medicine.

The researchers used two scanning techniques, atahanga te kōwarotanga autō (MRI) and diffusion tensor imaging (DTI), to examine the corpus callosum, the largest region of white matter, in the brains of 56 patients who had reported a first episode of psychosis, a 43 healthy volunteers from the local community.

The scans found that daily users of high-potency cannabis had a slightly greater – by about 2% – “mean diffusivity” in the corpus callosum. “That reflects a problem in the white matter that ultimately makes it less efficient,” Dazzan told the Guardian. “We don’t know exactly what it means for the person, but it suggests there is less efficient transfer of information.”

The study cannot confirm that high levels of THC in cannabis cause changes to white matter. As Dazzan notes, it is may be that people with damaged white matter are more likely to smoke skunk in the first place.

“It is possible that these people already have a different brain and they are more likely to use cannabis. But what we can say is if it’s high potency, and if you smoke frequently, your brain is different from the brain of someone who smokes normal cannabis, and from someone who doesn’t smoke cannabis at all,"Ka mea ia.

But even with the uncertainty over cause and effect, she urged users and public health workers to change how they think about cannabis use. “When it comes to alcohol, we are used to thinking about how much people drink, and whether they are drinking wine, pia, or whisky. We should think of cannabis in a similar way, in terms of THC and the different contents cannabis can have, and potentially the effects on health will be different,"Ka mea ia.

“As we have suggested previously, when assessing cannabis use, it is extremely important to gather information on how often and what type of cannabis is being used. These details can help quantify the risk of mental health problems and increase awareness of the type of damage these substances can do to the brain,” she added.

In February, Dazzan and others at the Institute of Psychiatry korerotia that the ready availability of skunk in south London might be behind a rise in the proportion of new cases of psychosis being attributed to cannabis.

guardian.co.uk © Guardian News & Media Limited 2010