maimoatanga o Alzheimer ofi rite mumura roro whakaaturia ki te kia matua

Alzheimer’s treatment closer as brain inflammation shown to be key

whakaatu Ako mahara me te whanonga raruraru mumura-whakaiti matū aukati atu i roto i te kiore mate, whakatairanga i tūmanako mō te maimoatanga tangata


Powered e Guardian.co.ukTēnei tuhinga ui “maimoatanga o Alzheimer ofi rite mumura roro whakaaturia ki te kia matua” e Ian etita Pūtaiao Tauira i tuhituhia, mo te Guardian ki Rāmere 8 January 2016 00.05 UTC

Scientists i tumanako hou mo te maimoatanga o te Alzheimer i muri ki ngā whakaiti mumura i roto i roro kiore mate mahara haukotia me raruraru whanonga i roto i te kararehe.

Kua roa te mate o Alzheimer kua hono ki te tauwhatinga i roto i te pūnaha ārai o te roro, engari tāpiri te rangahau hou ki te taunakitanga e mumura i roto i te roro e kore te pera nui meinga e te mate, engari ko te taraiwa o te whakararuraru,.

ako ngā kairangahau i University Southampton te kopa i hauora roro tangata me ētahi atu pāngia e te mate o Alzheimer. kitea ratou e i pūtau atu ārai roro o Alzheimer, mohiotia rite microglia, atu i roro hauora.

muri ka titiro nga pūtaiao i microglia i roto i kiore e kua muia ki te whakawhanake i tētahi tu'unga e rite te mate o Alzheimer. I roto i te raupapa o ngā korerotia i roto i te buka aamu Brain, te kapa patia kiore ki te matū e mutu tau microglia i tipu tiketike rawa.

I roto i te kiore kāore, te mate meinga pūtau roro tonu ki te ngaro ratou hononga ki tetahi ki tetahi. Otiia puritia kiore tukinotia ratou hononga io pūtau me i iti mahara, me ngā raruraru whanonga. Ua, tonu te maimoatanga nga taumata noa o microglia hiahiatia hoki te pūnaha ārai mate roro hauora. kihai i te maimoatanga, Heoi, mutu te hanga ki runga o āhuatanga whakatū papa amyloid i roto i te roro i te kararehe,.

Diego Gomez-Nicola, I arahi nei i te ako, ka mea ko nga ngā "rite tata ki te taunakitanga rite e nehenehe tatou e tiki" i nui hoki te ahunga whakamua o te mate o Alzheimer e mumura me microglia. Te kapa inaianei hiahia ki te mahi tahi me te ahumahi ho'oraa ki te kitea te tarukino tika e taea te whakamatautau i roto i te taata. Te matū hoatu ki te kiore mahi i runga i te receptor kitea i runga i te mata o microglia huaina CSFR1.

"Ko te pepa rawa whakaongaonga, me te pakari i te rōpū tino whakaaro o pūtaiao tenei,"Ka mea a Paora Morgan, kaiwhakahaere o Cardiff University a Systems papare University Research Institute. "Whakaara te kitenga te 'amanaki kiko o ngā CSFR1 whakahohenga ki tautāwhi i te whanaketanga o te tupu i roto i te hunga ki te tohu tuatahi o te mate o Alzheimer. No te mea kua taero e tautāwhi i CSFR1 faaitoitoraa i roto i te whare hauora hoki ētahi atu taupānga, ai nui atu hohoro kia tenei te whakatutuki atu i te tīmata i te wahanga ki te tarukino hou ".

Mark Dallas, he neuroscientist i University Reading, ka mea te kitea taea te whakamārama he aha i pera tawhiti taero hangaia ki te hamani Alzheimer o kua tutuki.

"I tenei rangahau pūtaiao taketake whakarato taunakitanga kaha, inaianei ka waiho i te wero ki te whakawhanake i rongoa mo te iwi ki te tupu. pinepine, kua tenei kua te tutukitanga waewae i roto i tahuri tirohanga i roto i te taiwhanga ki te therapy taea.

"Excitingly, e Heoi ngā reira huarahi hou mō ngā kairangahau ki te whakamahi me te haapuai te take mō te ngā i ētahi atu momo pūtau i roto i te roro i roto i te whawhai ki a Alzheimer o,"Ia tāpiri.

Haimona Ridley, kaiwhakahaere o te rangahau i te Alzheimer Rangahau UK, e tahi-pūtea te ako, mea: "Research rite tenei mea faufaa rite reira he wā kahore maimoatanga e taea mutu pōturi te ahunga whakamua o te mate o Alzheimer i roto i te roro ranei."

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