Pioneering kev kho mob cancer engineers muaj zog mus tua tus kab mob

Pioneering cancer treatment engineers immune systems to fight disease

 

Powered by Guardian.co.ukQhov tsab xov xwm hu ua “Pioneering kev kho mob cancer engineers muaj zog mus tua tus kab mob” raug sau los ntawm Haroon Siddique, rau theguardian.com on Wednesday 9 Hlis ntuj nqeg 2015 14.50 UTC

Cov neeg mob uas lub taub hau thiab lub caj dab mob cancer tau txais ib tug groundbreaking tshiab kev kho mob uas yuav tshoov siab lawv muaj zog rau sib ntaus sib tua tus kab mob no.

Mus sib hais, nyob rau National lub koom haum rau Health kev tshawb fawb biomedical kev tshawb fawb center ntawm txiv leej tub thiab St Thomas 'NHS foundation kev ntseeg siab thiab King kawm ntawv qib siab London, yuav kaw modifying cov neeg mob 'ntshav dawb kom lawv thiaj li paub txog thiab tua lub qog.

Ntshav dawb ntawm lub cev yog lawm nruab tshem tawm hlwb - tshwj xeeb tshaj yog kis tus kab mob sawv daws yuav - uas yuav tsum tsis txhob yuav muaj, tab sis tej zaum kuj xav tau kev pab kom paub txog thiab nres cancer hlwb.

Siv ib tug ntshav, lub BRC pab neeg no yog kho ntshav dawb nyob rau hauv lub laboratory nrog ib tug harmless kab mob uas qhia ob tug tshiab noob. Tus thawj noob ua rau nws yooj yim dua kom loj hlob lub hlwb thaum lub sij hawm lawv lub sij hawm nyob rau hauv lub laboratory thaum lub thib ob enables cov ntshav dawb kom paub txog thiab tawm tsam lub qog.

Tus thawj xib fwb neeg taug lw Dr John Maher hais tias: "Nyob rau hauv feem ntau cov qog nqaij hlav, metastasis, kis ntawm ib tug kab mob los ntawm ib sab ntawm lub cev qhov twg nws pib mus rau lwm lub tsis ncaj qha kev cob cog rua, yog lub commonest ua tuag. Txawm li cas los, lub taub hau thiab lub caj dab mob cancer yog txawv nyob rau hauv uas lub zos kis los yog rov muaj dua ntawm tus kab mob no tso nyiaj rau feem ntau raug kev txom nyem thiab kev tuag. Qhov no txhais tau tias hlav yuav ua inoperable thiab tsis ntsws nyob rau hauv cov lus teb rau cov tshuaj kho mob xws li cov kws khomob los yog radiotherapy. "

Cov kev kho mob no yog hu ua ib tug TSHEB T-cell thiab yuav siv sij hawm ob lub lis piam mus tsim. Yuav kom maximize nws muaj kev ruaj ntseg thiab cov hauj lwm zoo cov pab neeg no yog txhaj rau hauv lub TSHEB T-hlwb ncaj qha mus rau hauv lub qog. TSHEB T-cell kev kho mob tau proven zoo nyob rau hauv ib co ntaub ntawv ntawm leukemia, tiam sis qhov kev cia siab yog tias nws yuav tsum tsim ntxiv kom tau kev pab cov neeg mob uas thiaj li hu ua "khoom qog nqaij hlav", uas tsim ib tug discrete qog loj, xws li lub taub hau thiab lub caj dab mob cancer.

Maher hais tias kev vam meej yuav muaj "tseem ceeb cuam tshuam rau lwm yam khoom qog nqaij hlav, tshwj xeeb tshaj yog cov neeg uas kis tau nyob rau hauv ib natural qhov chaw nyob rau hauv lub cev, xws li ntawm zes qe menyuam cancer (hauv ob sab phlu ntawm lub plab mog) los yog Mesothelioma (hauv ob sab phlu ntawm lub ntsws). Nyob rau hauv uas qhov chaw, tej zaum nws yuav tsum tau mus txhaj cov TSHEB T-hlwb los ntawm tus neeg mob ncaj qha mus rau cov kab noj hniav, rau localize cov kev kho mob qhov twg nws yuav tsum tau feem ntau ".

Thaum lub sij hawm lub caij 1 mus sib, uas aims mus ntsuam xyuas cov kev kho mob txoj kev nyab xeeb thiab cov hauj lwm zoo, cov neeg mob muaj npe nyob hauv pab pawg yuav successively tau txais ib tug ntau dua tus naj npawb ntawm cov hlwb kom tsim muaj kev ruaj ntseg ntau npaum, muab nws tsis tsim teeb meem loj-phiv. Yog hais tias nws yog kev vam meej, cov kev kho mob yuav tsum tau yuav tsum tau mus soj ntsuam nyob rau hauv loj tus xov tooj ntawm cov neeg mob kom tsim yuav ua li cas zoo nws yog nyob rau combating cancer.

Dr Stephen Caddick, tus thawj coj ntawm kev nrhav ntawm lub Wellcome Trust, uas co-nyiaj mus sib, hais tias: "Los ntawm precision engineering tiv thaiv kab mob hlwb kom paub txog thiab ua kom puas hlav, soj ntsuam ntawm yog cia siab hais tias lawv yuav tsum tau los txhim kho lub zeem muag rau cov neeg mob uas muaj, kom txog rau thaum tam sim no, kev nyuaj siab heev tsawg kev kho mob. "

guardian.co.uk © Tus Saib Xyuas Xov xwm & Media Limited 2010

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