Farko da ciwon daji magani injiniyoyi na rigakafi da tsarin yãƙi cuta

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Powered by Guardian.co.ukWannan labarin mai taken “Farko da ciwon daji magani injiniyoyi na rigakafi da tsarin yãƙi cuta” aka rubuta ta hanyar Haroon siddiq, domin theguardian.com a ranar Laraba 9th Disamba 2015 14.50 UTC

Marasa lafiya da kai da wuya ciwon daji ana samun wani gawurtaccen sabon magani da ya shafi hakan ya sa su rigakafi da tsarin don su yi yaƙi da cutar.

A fitina, a National Institute for Health Research ilimin halittu da aikin likita bincike cibiyar a Guy ta kuma St Thomas 'NHS tushe dogara da Sarki ta College London, shafi genetically gyaggyarawa marasa lafiya 'farin jini Kwayoyin haka suka gane da kai farmaki da ƙari.

Farin jini Kwayoyin na rigakafi da tsarin da ake da sauƙi sanye take kawar da Kwayoyin - musamman kamu wadanda - cewa kada ta kasance a can, amma wani lokacin bukatar taimako don gane da harin da ciwon daji Kwayoyin.

Amfani da wani jini samfurin, da BRC tawagar da aka zalunta farin jini Kwayoyin a cikin dakin gwaje-gwaje da wani m cutar da cewa ya gabatar da biyu sabuwar genes. A farko gene sa ya fi sauƙi ga girma da sel a lokacin da lokaci a cikin dakin gwaje-gwaje yayin da na biyu damar da farin jini Kwayoyin don gane da kai farmaki da ƙari.

Principal binciken Dr John Maher ce: "A mafi cancers, metastasis, yaduwar wata cuta daga sashi na jikin inda ya fara zuwa wani ba kai tsaye alaka, ne commonest dalilin mutuwar. Duk da haka, kai da wuya ciwon daji ne sabon abu a cikin wannan gida baza ko komawa da cutar asusun for mafi wahala da mutuwa. Wannan yana nufin cewa marurai iya zama inoperable kuma ba ji ƙyama a mayar da martani ga gargajiya jiyya kamar jiyyar cutar sankara ko radiotherapy. "

A magani ne da ake kira a CAR T-cell da kuma daukan makonni biyu, don samar da. Don kara da aminci da kuma tasiri cikin tawagar da aka alura da CAR T-Kwayoyin kai tsaye a cikin ƙari. CAR T-cell magani ya tabbatar da tasiri a cikin wasu siffofin da cutar sankarar bargo amma bege shi ne cewa shi za a iya ci gaba da kara amfana marasa lafiya da ake kira "m cancers", wanda ya samar da wani mai hankali da ƙari taro, kamar kai da wuya ciwon daji.

Maher ce nasara za su iya "gagarumin abubuwan da wasu m cancers, musamman masu yada a cikin wata halitta sarari a cikin jiki, kamar ovarian ciwon daji (rufi na ciki) ko mesothelioma (rufi na huhu). A wannan saitin, shi iya yiwuwa a allurar CAR T-Kwayoyin daga haƙuri kai tsaye a cikin rami, to localize da magani inda shi ake bukata mafi ".

A lokacin da zamani 1 fitina, da nufin gwada magani da aminci da tasiri, marasa lafiya sa suna a cikin kungiyoyin za su samu nasarar samun wani mafi girma da dama Kwayoyin kafa hadari sashi, auren shi bai nuna gagarumin gefe-effects. Idan shi ne nasara, lura bukatar da za a jarraba a fi girma lambobin da marasa lafiya kafa yadda tasiri shi ne a wajen magance ciwon daji.

Dr Stephen Caddick, darektan bidi'o'i a da Wellcome Trust, wanda co-] a] en da fitina, ya ce: "By daidaici injiniya rigakafi Kwayoyin don gane, kuma ya halaka marurai, masu bincike suna fatan cewa za su iya inganta yiwuwa ga marasa lafiya da suke da, har yanzu, fuskanci sosai iyaka magani zažužžukan. "

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